Generic Name: dexamethasone intravitreal implant (DEX a METH a sone IN tra VIT ree al IM plant)
Brand Names: Ozurdex
What is dexamethasone intravitreal implant?
Dexamethasone is a steroid used to treat inflammation.
Dexamethasone intravitreal is an implant injected into the eye to treat swelling that may occur when there is a blockage of certain blood vessels in your eyes.
Dexamethasone intravitreal implant is also used to treat non-infectious uveitis affecting the posterior segment of the eye.
Dexamethasone intravitreal implant may also be used for purposes not listed in this medication guide.
What is the most important information I should know about dexamethasone intravitreal implant?
You should not receive this medication if you are allergic to dexamethasone (AK-Dex, Ocu-Dex, Cortastat, Dexasone, Solurex, Baycadron, DexPak, Zema Pak). You should not receive dexamethasone intravitreal implant if you have an eye infection or untreated glaucoma.
Dexamethasone intravitreal implant will be injected into your eye by healthcare professional in a clinic setting.
After the implant is put in place, you will be watched closely for any swelling or inflammation in your eyeball.
What should I discuss with my healthcare provider before receiving dexamethasone intravitreal implant?
You should not receive this medication if you are allergic to dexamethasone (AK-Dex, Ocu-Dex, Cortastat, Dexasone, Solurex, Baycadron, DexPak, Zema Pak), or if you have:
an eye infection; or
untreated glaucoma.
To make sure you can safely receive dexamethasone intravitreal implant, tell your doctor if you have ever had herpes infection of the eyes.
FDA pregnancy category C. It is not known whether dexamethasone intravitreal implant will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether dexamethasone intravitreal implant passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How is dexamethasone intravitreal implant given?
Dexamethasone intravitreal implant will be injected into your eye by healthcare professional in a clinic setting.
After the implant is put in place, you will be watched closely for any swelling or inflammation in your eyeball.
What happens if I miss a dose?
Since dexamethasone intravitreal is given as an implant by a healthcare professional, you will not be on a frequent dosing schedule.
What happens if I overdose?
Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.
What should I avoid after receiving dexamethasone intravitreal implant?
This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.
Dexamethasone intravitreal implant side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:
blurred vision, eye pain, or seeing halos around lights;
eye redness, increased sensitivity of your eyes to light; or
vision changes.
Less serious side effects may include blurred vision.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Dexamethasone intravitreal implant Dosing Information
Usual Adult Dose for Iritis:
For steroid responsive inflammatory ocular conditions:
Solution: For severe conditions, initially instill 1 to 2 drops in the lower conjunctival sac up to every hour during the day and every 2 hours during the night. Once improvement is observed, dosage may be decreased to 1 drop every 3 to 4 hours, then 1 drop 3 to 4 times daily.
Suspension: For severe conditions, instill 1 to 2 drops in the lower conjunctival sac up to every hour. Once improvement is observed, dosage may be decreased to 4 to 6 times daily, and gradually reduced further until discontinuation.
Ointment: Apply small amount to the conjunctiva 3 to 4 times a day. Once improvement is observed, may gradually reduce frequency before discontinuation.
Usual Adult Dose for Keratitis:
For steroid responsive inflammatory ocular conditions:
Solution: For severe conditions, initially instill 1 to 2 drops in the lower conjunctival sac up to every hour during the day and every 2 hours during the night. Once improvement is observed, dosage may be decreased to 1 drop every 3 to 4 hours, then 1 drop 3 to 4 times daily.
Suspension: For severe conditions, instill 1 to 2 drops in the lower conjunctival sac up to every hour. Once improvement is observed, dosage may be decreased to 4 to 6 times daily, and gradually reduced further until discontinuation.
Ointment: Apply small amount to the conjunctiva 3 to 4 times a day. Once improvement is observed, may gradually reduce frequency before discontinuation.
Usual Adult Dose for Conjunctivitis:
For steroid responsive inflammatory ocular conditions:
Solution: For severe conditions, initially instill 1 to 2 drops in the lower conjunctival sac up to every hour during the day and every 2 hours during the night. Once improvement is observed, dosage may be decreased to 1 drop every 3 to 4 hours, then 1 drop 3 to 4 times daily.
Suspension: For severe conditions, instill 1 to 2 drops in the lower conjunctival sac up to every hour. Once improvement is observed, dosage may be decreased to 4 to 6 times daily, and gradually reduced further until discontinuation.
Ointment: Apply small amount to the conjunctiva 3 to 4 times a day. Once improvement is observed, may gradually reduce frequency before discontinuation.
Usual Adult Dose for Cyclitis:
For steroid responsive inflammatory ocular conditions:
Solution: For severe conditions, initially instill 1 to 2 drops in the lower conjunctival sac up to every hour during the day and every 2 hours during the night. Once improvement is observed, dosage may be decreased to 1 drop every 3 to 4 hours, then 1 drop 3 to 4 times daily.
Suspension: For severe conditions, instill 1 to 2 drops in the lower conjunctival sac up to every hour. Once improvement is observed, dosage may be decreased to 4 to 6 times daily, and gradually reduced further until discontinuation.
Ointment: Apply small amount to the conjunctiva 3 to 4 times a day. Once improvement is observed, may gradually reduce frequency before discontinuation.
Usual Adult Dose for Acute Otitis Externa:
Instill 3 to 4 drops in the affected ear 2 to 3 times a day. Dosage may be reduced gradually as symptoms improve.
Alternatively, a cotton wick may be saturated with the solution or suspension and inserted into the ear canal. The wick should be kept moist with the ear drops and replaced every 12 to 24 hours.
Usual Adult Dose for Uveitis:
For the treatment of macular edema following branch retinal vein occlusion (BRVO) or central retinal vein occlusion (CRVO) and for the treatment of noninfectious uveitis affecting the posterior segment of the eye:
1 implant, containing 0.7 mg of dexamethasone, to be surgically injected into the vitreous cavity of the affected eye.
Usual Adult Dose for Macular Edema:
For the treatment of macular edema following branch retinal vein occlusion (BRVO) or central retinal vein occlusion (CRVO) and for the treatment of noninfectious uveitis affecting the posterior segment of the eye:
1 implant, containing 0.7 mg of dexamethasone, to be surgically injected into the vitreous cavity of the affected eye.
Usual Pediatric Dose for Iritis:
1 year or older: For steroid responsive inflammatory ocular conditions:
Solution: For severe conditions, initially instill 1 to 2 drops in the lower conjunctival sac up to every hour during the day and every 2 hours during the night. Once improvement is observed, dosage may be decreased to 1 drop every 3 to 4 hours, then 1 drop 3 to 4 times daily.
Suspension: For severe conditions, instill 1 to 2 drops in the lower conjunctival sac up to every hour. Once improvement is observed, dosage may be decreased to 4 to 6 times daily, and gradually reduced further until discontinuation.
Ointment: Apply small amount to the conjunctiva 3 to 4 times a day. Once improvement is observed, may gradually reduce frequency before discontinuation.
Usual Pediatric Dose for Keratitis:
1 year or older: For steroid responsive inflammatory ocular conditions:
Solution: For severe conditions, initially instill 1 to 2 drops in the lower conjunctival sac up to every hour during the day and every 2 hours during the night. Once improvement is observed, dosage may be decreased to 1 drop every 3 to 4 hours, then 1 drop 3 to 4 times daily.
Suspension: For severe conditions, instill 1 to 2 drops in the lower conjunctival sac up to every hour. Once improvement is observed, dosage may be decreased to 4 to 6 times daily, and gradually reduced further until discontinuation.
Ointment: Apply small amount to the conjunctiva 3 to 4 times a day. Once improvement is observed, may gradually reduce frequency before discontinuation.
Usual Pediatric Dose for Conjunctivitis:
1 year or older: For steroid responsive inflammatory ocular conditions:
Solution: For severe conditions, initially instill 1 to 2 drops in the lower conjunctival sac up to every hour during the day and every 2 hours during the night. Once improvement is observed, dosage may be decreased to 1 drop every 3 to 4 hours, then 1 drop 3 to 4 times daily.
Suspension: For severe conditions, instill 1 to 2 drops in the lower conjunctival sac up to every hour. Once improvement is observed, dosage may be decreased to 4 to 6 times daily, and gradually reduced further until discontinuation.
Ointment: Apply small amount to the conjunctiva 3 to 4 times a day. Once improvement is observed, may gradually reduce frequency before discontinuation.
Usual Pediatric Dose for Cyclitis:
1 year or older: For steroid responsive inflammatory ocular conditions:
Solution: For severe conditions, initially instill 1 to 2 drops in the lower conjunctival sac up to every hour during the day and every 2 hours during the night. Once improvement is observed, dosage may be decreased to 1 drop every 3 to 4 hours, then 1 drop 3 to 4 times daily.
Suspension: For severe conditions, instill 1 to 2 drops in the lower conjunctival sac up to every hour. Once improvement is observed, dosage may be decreased to 4 to 6 times daily, and gradually reduced further until discontinuation.
Ointment: Apply small amount to the conjunctiva 3 to 4 times a day. Once improvement is observed, may gradually reduce frequency before discontinuation.
Usual Pediatric Dose for Acute Otitis Externa:
1 year or older:
Instill 3 to 4 drops in the affected ear 2 to 3 times a day. Dosage may be reduced gradually as symptoms improve.
Alternatively, a cotton wick may be saturated with the solution or suspension and inserted into the ear canal. The wick should be kept moist with the ear drops and replaced every 12 to 24 hours.
What other drugs will affect dexamethasone intravitreal implant?
It is not likely that other drugs you take orally or inject will have an effect on dexamethasone used in the eyes. But many drugs can interact with each other. Tell your doctor about all medicines you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
More dexamethasone intravitreal implant resources
- Dexamethasone intravitreal implant Use in Pregnancy & Breastfeeding
- Dexamethasone intravitreal implant Drug Interactions
- Dexamethasone intravitreal implant Support Group
- 0 Reviews for Dexamethasone intravitreal - Add your own review/rating
Compare dexamethasone intravitreal implant with other medications
- Acute Otitis Externa
- Conjunctivitis
- Cyclitis
- Iritis
- Keratitis
- Macular Edema
- Uveitis
- Uveitis, Posterior
Where can I get more information?
- Your doctor or pharmacist can provide more information about dexamethasone intravitreal implant.
No comments:
Post a Comment